Improved survival for skin-primary presentation of adult T-cell leukemia/lymphoma (ATLL)
نویسندگان
چکیده
منابع مشابه
Adult T-cell leukemia/lymphoma (ATLL)
Pathogenesis of the disease: ATLL is associated with HTLV-1 infection of the tumour clone in 100% of the cases. The interval between HTLV-1 infection and the onset of lymphoma is long (10-40 years) and only <5% of infected people actually develops the disease. HTLV-1 produces a trans-regulatory protein (Tax) inducing interleukin-2 (IL-2) and IL-2 receptor expression and consequent polyclonal CD...
متن کامل[Clinical aspects of adult T-cell leukemia-lymphoma (ATLL). (1) Survival rate and prognosis of adult T-cell leukemia].
We screened serum samples from patients with various hematological disorders and healthy individuals for the presence of adult T-cell leukemia/lymphoma associated antigen (anti-ATLA) antibodies. These antibodies were detected not only in all patients with ATL but frequently in those diagnosed as T-cell malignant lymphoma or T-cell chronic lymphocytic leukemia; the positivity rate of anti-ATLA a...
متن کاملA case report of adult T-cell leukaemia/lymphoma (ATLL).
Adult T-cell leukaemia/lymphoma (ATLL) is a unique disease with distinct manifestations, a characteristic phenotype and a likely retroviral aetiology. It is unusual in Southeast Asia, though more commonly seen in some countries like Japan. We report a case of this disease in a 71-year-old man in Singapore who presented with papular erythematous eruptions for 6 years and subsequently developed g...
متن کاملAdult T-cell leukaemia/lymphoma (ATLL) and T-cell leukemia virus type 1 (HTLV1)
Epidemiology The disease has a long latency, and affected individuals usually are exposed to the virus very early in life. The virus may be transmitted in breast milk, and through exposure to blood and blood products. The cumulative incidence of ATLL is estimated to be 2.5% among HTLV-1 carriers in Japan (1). Sporadic cases have been found in the United State and elsewhere. It occurs in adults ...
متن کاملUnusual Presentation of T-cell non-Hodgkin Lymphoma with Multiple Skin Nodules
Non-Hodgkin lymphoma is very uncommon in infancy and skin as the primary site of involvement in Non-Hodgkin lymphoma is rarely encountered. We describe a 10-month-old infant with T-cell Non-Hodgkin lymphoma who presented with multiple skin nodules as the predominant feature of her disease. The clinical manifestations, treatment strategy and disease outcome are reviewed. Key words: Non-Hodgk...
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ژورنال
عنوان ژورنال: Journal of the American Academy of Dermatology
سال: 2020
ISSN: 0190-9622
DOI: 10.1016/j.jaad.2019.11.034